The Mineralogy Collection is located in the Department of Earth and Marine Sciences and houses one of the richest and oldest collections of minerals in Sicily, such as the splendid finds of the Sicilian gypsum-sulphur series, the various collections of minerals, often rare and from all continents, the rocks and decorative stone materials, the precious Sicilian amber, the precious and ancient nineteenth-century study and research tools.
In the new layout, the logic of the route is that of a journey inside the matter, trying to attribute a new meaning and a new location to each piece: from the micro to the macro, from meteorites from a very distant space-time to the atom, with the idea of allowing the visitor to codify the structures of "life" and "system" of each piece within an overall vision, that of the government of the laws of nature and principles.

The collection was born from the initial nucleus of the donation of Baron Cesare Airoldi, which included geological and paleontological finds and arrived at the University's Institute of Geology in the mid-nineteenth century. It is a collection that still adheres to the criteria of collecting, rather than to a scientific naturalistic interest. The other collections kept in the Institute can be ascribed mostly to the Miocene period and to the gypsum-sulphurous area of the region.